Regulatory Note: This is a generic alternative manufactured in India. The original branded version received FDA approval.
If you are someone who suffers from erectile dysfunction, then you have come across the names Viagra and Revatio. Most people often wonder why two medications seem so similar yet are used in very different ways. Both contain the same active ingredient, Sildenafil, but they are prescribed for completely different conditions and come in different doses and formulations. This often leads to confusion.
In this article, we will break down the key differences between Revatio and Viagra so you can clearly understand how they work and why they are not interchangeable.
Key Points
- Revatio and Viagra both contain the active ingredient Sildenafil and are marketed by Pfizer for erectile dysfunction and pulmonary arterial hypertension. Revatio is generally administered at lower doses three times a day, and Viagra at higher doses once before sexual activity.
- Both medications are part of the Phosphodiesterase-5 (PDE5) inhibitor class, which works by dilating the blood vessels. They are both prescribed for different conditions, based on their dosage and form.
- The active ingredient in both drugs is Sildenafil Citrate. It has been proven in clinical trials to improve the symptoms of pulmonary arterial hypertension and erectile dysfunction, depending on specific conditions being treated.
Introduction To Revatio And Viagra
Revatio and Viagra are two widely recognized medications containing the same active ingredient, Sildenafil. While they are chemically identical, they are approved for different medical indications and are used in distinct therapeutic contexts.
Viagra is prescribed for the treatment of Erectile Dysfunction in men, where it works by enhancing blood flow to support the achievement and maintenance of an erection. This brand medicine is also available in a generic option, such as Cenforce, Malegra, and Aurogra.
On the other hand, Revatio is prescribed for the management of pulmonary arterial hypertension, a serious condition affecting the blood vessels in the lungs and heart.
What Are The Differences Between Revatio And Viagra?
The common differences between Revatio and Viagra include-
Medical Purpose
Viagra is prescribed for the treatment of Erectile Dysfunction. It helps improve blood flow to the penis, allowing men to achieve and maintain an erection during sexual activity. Whereas Revatio is used to treat pulmonary arterial hypertension (PAH), a condition that causes high blood pressure in the arteries of the lungs. It works by relaxing blood vessels in the lungs to improve blood flow and reduce strain on the heart.
Dosage Strength
Viagra is typically prescribed in higher doses, commonly 25 mg, 50 mg, or 100 mg, and is taken as needed before sexual activity. Further, Generic Viagra tablets are also available in high doses such as 200mg.
Revatio, however, is usually prescribed in lower doses (such as 20 mg) and is taken multiple times a day on a regular schedule for ongoing management of PAH.
How They Are Used
Viagra is taken only when required, usually about 30 to 60 minutes before sexual activity, and its effects last for 4 to 6 hours. Whereas Revatio is taken consistently throughout the day as part of a long-term treatment plan.
Key Clinical Difference
The most important difference is not the ingredient but the treatment goal: Viagra is used to support sexual function, while Revatio is used to manage a serious cardiovascular and respiratory condition.
Revatio Vs. Viagra: Which Is More Effective?

Both Revatio and Viagra contain the same active ingredient, Sildenafil Citrate. Since the brand names are marketed for different purposes, they are effective in their own way. Overall, Sildenafil has been shown by clinical trials to be safe and effective.
In a systematic review of the efficacy and safety of sildenafil treatment in PAH, the treatment with Sildenafil for 12 weeks or more improved the clinical symptoms of pulmonary hypertension. Sildenafil was also found to delay disease progression in adults.
Another similar review stated that men with erectile dysfunction, Sildenafil was found to be effective and well-tolerated. Sildenafil helped to improve erectile dysfunction with generally mild side effects. It is especially helpful for men with Peyronie’s disease, a penile tissue disorder where scar tissue can cause the penis to bend abnormally.
Depending upon your condition, Revatio or Viagra might be prescribed. Always consult your doctor to determine which treatment may work best for you.
What Are The Common Side Effects Of Revatio And Viagra?
The common side effects of Sildenafil are:
- Headache.
- Indigestion.
- Flushing.
Depending on different clinical trials, those who take Revatio might experience other side effects such as:
- Insomnia.
- Shortness of breath.
- Diarrhea.
- Nasal congestion.
- Muscle pain.
Other Common side effects of Viagra include-
- Nasal congestion.
- Back pain.
- Muscle pain.
- Nausea.
- Dizziness.
- Rash.
Serious side effects of Sildenafil might also include:
- Blurred vision.
- Hearing loss.
- Priapism.
- Chest pain.
- Stroke
- Low blood pressure.
It is always advised to consult with your doctor for proper guidance and treatment.
Revatio Vs. Viagra: Drug Interactions
Taking Revatio and Viagra with other medicines and supplements can result in a drug interaction. This can lower the effectivness of the medicine and increase the risk of side effects. Some of the drug interactions of the active ingredient Sildenafil Citrate are:
- Azole.
- Clarithromycin.
- Grapefruit juice.
- Norvir.
- Antibiotics such as Cipro and Levaquin.
- Tegretol.
- Dilantin.
- Rimactane.
- Saint-John’s-Wort.
You should never take Revatio or Viagra with nitrate-based medications such as nitroglycerin, as it can lead to a sudden drop in blood pressure.
Revatio Vs. Viagra: Warnings And Precautions
The following are the precautions and warnings that are to be followed while taking Revatio and Viagra:
- Revatio and Viagra might affect blood pressure, and their use should be cautioned in individuals with low blood pressure or on medication for high blood pressure.
- People with heart disease or who take medications for chest pain might need to take special precautions.
- Taking Sildenafil might increase the risk of worsening heart disease, chest pain, or heart attacks in severe cases.
- Some users of Revatio or Viagra have experienced a condition called anterior ischemic optic neuropathy (AION). The decrease or sudden loss of vision characterizes the condition.
Priapism is a persistent and painful erection that lasts longer than 4 hours. It is a rare side effect associated with Sildenafil. Whenever you experience an adverse impact, seek medical attention immediately.
How To Choose Between Revatio Vs. Viagra
Choosing between them is not about preference, but about the specific condition being treated and a doctor’s recommendation.
If the concern is Erectile Dysfunction, Viagra or its generic versions are typically prescribed. Revatio, on the other hand, is strictly used for pulmonary arterial hypertension and should not be used as a substitute for ED treatment.
For those looking for a more affordable option for ED treatment, it is important to discuss this with a healthcare provider about generic options. Your doctor may often start with lower doses, such as Cenforce 100 mg, to evaluate how the medication works for your body and adjust the dosage if needed.
The safest and most effective choice depends on medical guidance, individual response, and proper dosage adjustment rather than self-selection between these medications.
Conclusion
Revatio and Viagra both contain the same active ingredient, Sildenafil. However, they are used to treat different conditions. Revatio is prescribed for people with Pulmonary Arterial Hypertension (PAH). This helps improve their exercise ability and reduce shortness of breath.
Viagra, on the other hand, is used for individuals who have difficulty getting and maintaining an erection during sexual activity. Both medications work by widening the blood vessels. This can lower the blood pressure in the lungs or increase the blood flow in the penis.
You must consult with a healthcare provider to ensure you receive the proper medication for the specific condition you need to manage.
Disclaimer:
All information provided is for informational purposes only. This is not a substitute for professional medical advice.
FAQs
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References
- Revatio Vs. Viagra, verywellhealth
- Revatio Vs. Viagra, singlecare
- Revatio Vs. Viagra, What’s Difference

